More than seven years ago Albert J. Sinusas, MD, a professor of medicine, radiology, and biomedical engineering, was working with a team of engineers for development of an imageable polymer for prevention of adverse remodeling after a heart attack when they inadvertently discovered that when iodine, a contrast agent used for X-ray imaging, is packed in a nanoparticle there is greater absorption of X-rays potentially improving visibility.
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Source: Phys.org