CRISPR-Cas components work together to enhance protection from viruses

Researchers from Skoltech and their colleagues from Russia and the U.S. have shown that the two components of the bacterial CRISPR-Cas immunity system, one that destroys foreign genetic elements such as viruses and another that creates “memories” of foreign genetic elements by storing fragments of their DNA in a special location of bacterial genome, are physically linked. This link helps bacteria to efficiently update their immune memory when infected by mutant viruses that learned to evade the CRISPR-Cas defense. The paper was published in the journal Proceedings of the National Academy of Sciences.


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Source: Phys.org