A longstanding basic question in biology relates to how life satisfies the fundamental constraints put on it by physics and chemistry. Darwin’s warm pond hypothesis for the origin of primordial cells is a familiar one. Advances have been made in mapping out the organic molecules that likely existed on the early Earth, and recently candidate prototypic pathways in early cells have been formulated. But how did these candidates’ early biochemistry actually function as a system on which subsequent cellular life is based?
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Source: Phys.org