Stronger together: How protein filaments interact

Just as the skeleton and muscles move the human body and hold its shape, all the cells of the body are stabilized and moved by a cellular skeleton. Unlike the vertebrate skeleton, this cellular skeleton is a very dynamic structure, constantly changing and renewing itself. It consists of different types of protein filaments, which include intermediate filaments and microtubules. Now, a research team from the University of Göttingen has observed a direct interaction between microtubules and intermediate filaments outside the cell, and quantitatively measured this interaction. The results of the study were published in Nature Communications.

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