The endosome has highly dynamic motility and frequently undergoes fission and fusion events to coordinate endocytic trafficking. Endosome fission has been reported to be associated with cargo sorting. After internalization, cargoes can be segregated into distinct domains allocated for their destination, proceeding to either lysosomes for degradation, or the plasma membrane or trans-Golgi network (TGN) for recycling.
Click here for original story, Researchers discover Golgi-derived vesicle regulating endosome fission
Source: Phys.org