Iridium-catalyzed hydrogen addition, giving plant- and insect-based natural substances

The cost-effectiveness of drug synthesis depends on a number of factors, including the amount of waste produced. A team of researchers have now discovered a catalyst that achieves exceptionally high-precision addition of hydrogen to carbon-carbon bonds, improving targeted synthesis by avoiding convoluted multi-step processes, and reducing wasteful by-products. In the journal Angewandte Chemie, the authors herald the reaction as especially useful in the production of complex natural substances such as pheromones.


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Source: Phys.org