In the latest of ongoing efforts to expand technologies for modifying genes and their expression, researchers in the lab of Neville Sanjana at New York University (NYU) and the New York Genome Center (NYGC) have developed chemically modified guide RNAs for a CRISPR system that targets RNA instead of DNA. These chemically modified guide RNAs significantly enhance the ability to target—trace, edit, and/or knockdown—RNA in human cells.
Click here for original story, Scientists boost gene knockdown in human cells with CRISPR-Cas13 using chemically modified guide RNAs
Source: Phys.org