Study reveals structure of receptor implicated in type 2 diabetes and more

Researchers from the University of Southern California, Merck & Co., Skoltech, MIPT, UCLA, and the Université de Sherbrooke have determined the structure of the human leukotriene B4 receptor 1, involved in inflammatory, infectious, allergic, and tumorigenic diseases. Published in Nature Communications, the analysis of the structure reveals how the receptor recognizes its binding partners and interacts with them. This opens up avenues for designing better drugs that would target the receptor to treat Type 2 diabetes and other pathologies.


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Source: Phys.org