A preclinical study has analyzed the interactions of the lipid mediator sphingosine-1-phosphate (S1P) in the spleen and heart during the transition from acute to chronic heart failure. Using a mouse model of heart failure, the researchers discovered new mechanisms to help define how the spleen and heart coordinate physiological inflammation in cardiac repair.
Click here for original story, Preclinical study defines the spleen-heart connection in cardiac repair
Source: ScienceDaily