A sequence change in a single protein allowed a tomato virus to become a global crop pandemic

In the last years, a new viral tomato disease has emerged, threatening tomato production worldwide. This is caused by the Tomato brown rugose fruit virus (ToBRFV), a member of a devastating group of plant viruses called tobamoviruses. ToBRFV overcomes all known tobamovirus resistance in tomato, including the one conferred by Tm-22, a resistance gene responsible for the stable resistance to these viruses for more than 60 years. In a study recently published in the Molecular Plant-Microbe Interactions (MPMI), journal, Dr. Ziv Spiegelman and Dr. Hagit Hak explored the molecular mechanism by which this emerging virus was able to successfully break this resistance and become a devastating global crop pandemic.


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Source: Phys.org