Exogenous artificial DNA forms chromatin structure with active transcription in yeast

Previously, researchers from Tianjin University designed and created a 254 kb digital data carrying artificial chromosome in yeast. This work “is a key proof-of-concept that demonstrated how artificial chromosomes can be used for data storage in a way that is robust and essentially free to copy.” It broke through the limitation for the total length of encoded data within a single cell of just a few thousand base pairs per genome. The intracellular biological characteristics of this completely exogenous digital data-carrying chromosome (dChr) have received widespread attention.


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Source: Phys.org