Understanding how autoactivation triggers cell death

Apoptosis is a process that causes cell death. It can go awry in cancer cells, sustaining the disease. Scientists at St. Jude Children’s Research Hospital have captured the structure of BAK, a protein that triggers apoptosis. They have shown how BAK autoactivates, essentially turning itself on. Understanding how apoptosis is triggered can lead to drugs that kill cancer cells. The findings were published online today in Nature Communications.


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Source: Phys.org