Morphological fingerprinting could help identify side effects and new bioactive compounds in drug discovery

Pharmaceutical researchers speak of a hit when they come across a promising substance with a desired effect in early drug discovery. Unfortunately, hits are rarely bull’s-eyes, often showing undesirable side effects that not only complicate the search for new hits, but also the subsequent development into a drug. A new study by Slava Ziegler and Herbert Waldmann from the Max Planck Institute of Molecular Physiology in Dortmund could now help to better identify one of the most frequently observed side effects already in early drug discovery, but also to find new bioactivities.


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Source: Phys.org