New, targeted method for probing the function of 3D chromosomal structure

A new method that can induce interactions between specifically chosen locations on the genome allows researchers to begin to identify the causal relationship between three-dimensional chromosome structure and genome function. A paper by researchers at Penn State describing the method, called “chemically induced chromosomal interaction (CICI),” and two functional tests of the method appears Feb. 9 in the journal Nature Communications.


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Source: Phys.org