Patented molecules that counteract the effect of the most common anticoagulant drug

A study performed by researchers from the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) from the Spanish National Research Council (CSIC) has discovered and synthesized several molecules that inhibit the effect of the most common anticoagulant drug. This drug is very useful for treating patients at risk of thrombi, but on many occasions it is essential to block its action when these patients face surgical interventions to avoid uncontrolled bleeding. Two of these molecules have been tested, with very good results, in assays with mice, which could be the first step to design possible drugs. These results have been patented and published in The Journal of Medicinal Chemistry (ACS).


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Source: Phys.org