DNA methylation is a major epigenetic modification that is crucial for mammalian development. For instance, DNA methylation is central to inexhaustible biological processes, such as gene regulation and cell fate decisions. In mammals, DNA methyltransferases are key for blastocysts to re-establish global DNA methylation patterns during implantation. This is critical for passing on epigenetic information to the next generation.
Click here for original story, A single allele deletion in gene encoding Zbtb38 leads to early embryonic death
Source: Phys.org