Hypertrophic cardiomyopathy is a heart disease that leads to a stressed, swollen heart muscle. Due to a poor understanding of underlying mechanisms, effective clinical treatments are not available. Patients receive generic heart medication and sometimes need open-heart surgery to remove excess tissue. Researchers have now successfully applied a new revolutionary technology (scRNA-seq) to uncover underlying disease mechanisms, including specifically those causing the swelling. The extensive ‘big data’ set is a treasure trove of novel observations that give insight in hypertrophic cardiomyopathy and potential new therapeutic venues.
Click here for original story, Single cell RNA sequencing uncovers new mechanisms of heart disease
Source: ScienceDaily