Heart progenitors spontaneously regenerate cardiac muscle via a tight junction 'honeycomb' in salamanders

Whether there are endogenous adult heart progenitors that can replenish damaged muscle cells remained controversial. Now researchers at Karolinska Institute in Sweden show that the outermost layer of the heart, called epicardium, acts as a source of cardiac muscle cells through formation of an intriguing honeycomb-like structure.


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Source: Phys.org