Kobe University researchers have successfully developed a tyrosine chassis (a strain of microorganism with high tyrosine productivity) in the yeast Pichia pastoris through rational engineering. In addition they used this tyrosine chassis to develop smart cells that can produce the plant-derived compounds resveratrol, naringenin, norcoclaurine, and reticuline respectively. These compounds have a wide range of applications; for example they are used to add nutrition to foods and as raw materials for medicines. It is hoped that this tyrosine chassis can be used as a starting point for high-yield biosynthesis of various useful compounds and generic chemicals.
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Source: Phys.org