A more sustainable use of chemical resources is part of the United Nations’ Agenda 2030. Synthetic chemists are therefore working to design and carry out efficient syntheses. Within the synthetic organic chemist’s arsenal, processes that link several molecules (coupling partners) in a single step—so-called multi-component reactions (MCRs)—play a central role. These are considered sustainable and environmentally friendly technologies for the rapid production of complex structures and drugs in a single reaction step. A team of researchers led by chemistry professor Frank Glorius (University of Münster) and Dr. Huan-Ming Huang (University of Münster and ShanghaiTech University) has now succeeded for the first time in using so-called ketyl radicals for a novel MCR. This study was published in the recently founded journal Nature Synthesis.
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Source: Phys.org