A group of Skoltech researchers under Dr. Olga Sergeeva’s supervision studied the functions of a long non-coding RNA, which is “read” from the genome, but does not carry the information about protein structure. In experiments on animals and cell lines, scientists have shown that long non-coding RNA LL35 regulates the metabolism of glucose and lipids. Moreover, its depletion suppresses liver cells’ ability to migrate and divide normally. These results make this long non-coding RNA a potential target for diagnosis and therapy. The details of the study are described in detail in an article published in the journal Biomedicines.
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Source: Phys.org