The maternal-to-zygotic transition, involving maternal mRNA clearance and zygotic genome activation (ZGA), is a conserved and fundamental process during vertebrate embryogenesis. During this critical developmental period, the embryo undergoes dramatic reprogramming by switching from a maternal factor-dominated state to a zygotic factor-driven state. Due to the transcriptional quiescence of the zygotic genome during the initial developmental stages, selective maintenance and translational control of maternal mRNAs are essential.
Click here for original story, Mechanism of maternal-to-zygotic transition in zebrafish found in phase separation of enzyme
Source: Phys.org