Some of the toughest challenges in treating disease are presented by “undruggable” proteins whose structures and roles in disease are known but are seemingly unable to be targeted by drugs that will bind to them. Researchers at KAUST have now shown that the molecular motion of many “undruggable” proteins can in fact expose sites at which drugs could bind.
Click here for original story, Molecular motion of proteins reveals previously unseen binding sites that could be targets for new drug molecules
Source: Phys.org