A study expands the list of known genes with circadian variation and provides the first comprehensive list of genes with seasonal variation in each tissue. Tissues in the thoracic cavity, such as the lung and heart, were most sensitive to day-night cycles, while the brain and testes were most sensitive to seasonal changes. The researchers identified 91 day-night genes and 307 seasonal genes that are known-targets for drugs, including 11 chemotherapies. The drugs could benefit from being administered in a time or season-dependent manner.
Click here for original story, Seasonal and circadian genetic variation charted across the human body
Source: ScienceDaily