In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture sequencing. Still, the direct visualization of the coiled chromonema confirming the helical model was lacking. Now, an international research team provides the direct proof of the helical coiling of condensed chromatids via super-resolution microscopy of specifically labelled chromonema regions.
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Source: ScienceDaily