Bones remain healthy thanks to the fact that they are continuously remodeling, a process dependent on the balance between the activity of osteoblasts—cells that create bone tissue—and the osteoclasts, which reabsorb it. An imbalance between these two can disrupt bone homeostasis and lead to diseases such as osteopenia, which is a loss of bone mass.
Click here for original story, Researchers find HERC1 protein deficiency causes osteopenia
Source: Phys.org