A condition called CD3 delta SCID is caused by a mutation in the CD3D gene, which prevents the production of the CD3 delta protein that is needed for the normal development of T cells from blood stem cells. Researchers showed that a new genome editing technique called base editing can correct the mutation that causes CD3 delta SCID in blood stem cells and restore their ability to produce T cells. Base editing is an ultraprecise form of genome editing that enables scientists to correct single-letter mutations in DNA.
Click here for original story, Study uses base editing to correct mutation that causes rare immune deficiency
Source: ScienceDaily