An extra gene increases inhibitory signaling in the brain of the Down syndrome mouse

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues. The finding may help explain some of the neurologic consequences of the syndrome.


Click here for original story, An extra gene increases inhibitory signaling in the brain of the Down syndrome mouse


Source: Phys.org