Optimized prime editing alters genes of living mice, marking major advance

Harvard University researchers have improved a gene editing process for studying and treating genetic disorders. The prime editing method is effective in human cells, targeting single nucleotide variants with the ability to precisely correct pathogenic mutations or install more protective variants. While success in the lab has been promising, translating these effects into living systems where the therapeutic potential could be unleashed has proven tricky.


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Source: Phys.org