Mammalian mitochondrial translation requires fidelity mediated by proofreading function of threonyl-tRNA synthetase

In a study published in PNAS, the team led by Prof. Zhou Xiaolong and Prof. Wang Enduo from the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences report that mammalian mitochondrial translation requires a high-level of accuracy at Thr codons, which is mediated by the proofreading (editing) function of mitochondrial threonyl-tRNA synthetase (mtThrRS).


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Source: Phys.org