Pancreatic β-cells are essential for secreting insulin to regulate glucose homeostasis. During metabolic stress they respond by increasing insulin production and secretion and proliferation to meet the increased metabolic demand. A detailed understanding of this process is important to understand the processes leading to β-cell decompensation and demise in obesity and type 2 diabetes.
Click here for original story, Protein coding gene coordinates cell division, protein synthesis, and mitochondrial activity in β-cells
Source: Phys.org