Cell Biology Experiment Facility (CBEF) Centrifuge Remove and Replace (R&R): The crew was scheduled to remove the 1G centrifuge from the CBEF and install a new centrifuge. However, the bag with the new centrifuge could not be found. Teams are investigating impacts to downstream science and opportunities to launch replacement hardware. The CBEF is a Japan Aerospace Exploration Agency (JAXA) subrack facility located in the Saibo (living cell) Experiment Rack. The CBEF is used in various life science experiments, such as cultivating cells and plants in the Japanese Experiment Module (JEM). Fluid Shifts: Today, FE-1 performed his Flight Day 45 baseline imaging for the Fluid Shifts experiment. With assistance from another crewmember as the onboard imager and ground remote guidance, ultrasound imaging was taken of arterial and venous measures of the head and neck, cardiac, ophthalmic and portal vein, and tissue thickness of lower and upper body. Additional measurements using the Cerebral and Cochlear Fluid Pressure (CCFP), Distortion Product Otoacoustic Emissions (DPOAE), Optical Coherence Tomography (OCT), ESA’s Cardiolab (CDL) Holter Arterial Blood Pressure Device, and Intraocular Pressure (IOP) using the tonometer were taken as well. Fluid Shifts is a joint NASA-Russian experiment that investigates the causes for severe and lasting physical changes to astronaut’s eyes. Because the headward fluid shift is a hypothesized contributor to these changes, reversing this fluid shift with a lower body negative pressure device is investigated as a possible intervention. Results from this study may help to develop preventative measures against lasting changes in vision and eye damage. Portable Emergency Provisions (PEPS) Inspection: The crew inspected and confirmed that the Portable Fire Extinguishers (PFEs), Extension Hose Tee Kits (EHTKs), Portable Breathing Apparatuses (PBAs) and Pre-Breathe Masks are all free of damage. This maintenance is scheduled every 45 days to ensure continuous functionality of the units. Today’s Planned Activities All activities were completed unless otherwise noted. Biochemical urine test KORREKTSIYA. Collection of Blood Samples KORREKTSIYA. Closeout Ops KORREKTSIYA. Venous blood sample processing using Plasma-03 centrifuge Insertion of Russian experiments blood samples into MELFI KORREKTSIYA. Handover to USOS for MELFI Insertion URISYS Hardware Stowage KORREKTSIYA. Logging Liquid and Food (Medicine) Intake Story Time Why So Fast Read Story Time From Space Historical Photo 24-hour ECG Holter Monitoring – term Cell Biology Experiment Facility (CBEF) Centrifuge Removal [Aborted] Fluid Shifts OCT Baseline Setup Fluid Shifts Ultrasound 2 HRF Rack 1 Power On Fluid Shifts CDL Holter Arterial BP Hardware Don 24-hour ECG Holter Monitoring – term Replacement of [СРВ-К2М] Control Panel. ISS Crew Adaptation Fine Motor Skills Experiment Test Fluid Shifts Ultrasound Baseline Scan Soyuz 733 Transfers and IMS Ops Cell Biology Experiment Facility (CBEF) Centrifuge Installation [Aborted] Fluid Shifts CCFP Baseline Test Fluid Shifts USOS Operations Historical Documentation Photography [Aborted] Columbus ENERGY Stowage Repack Multi-user Droplet Combustion Apparatus Session Review Fluid Shifts OCT Baseline Exam ISS Crew Orientation Saibo Rack Remote Sensor Unit (RSU) Cable Reconfiguration Cell Biology Experiment Facility (CBEF) Plant Experiment Unit 1G Installation [Aborted] Fluid Shifts DPOAE Baseline Test Fluid Shifts OCT Baseline Stow Fluid Shifts Tonometry Baseline Setup Environmental Health System (EHS) Grab Sample Container (GSC) Sampling Operations Fluid Shifts Tonometry Baseline Exam Fluid Shifts CDL Holter Arterial BP Hardware Doff ПТАБ-1М Temperature Check (pos. А308). Fluid Shifts CCFP Baseline Stow Food Frequency Questionnaire (FFQ) or ISS Food Intake Tracker (ISS FIT) Water Resource Management (WRM) Condensate Sample Init KORREKTSIYA. Logging Liquid and Food (Medicine) Intake Download Pille Dosimeter Readings СОЖ maintenance Combustion Integrated Rack Hardware Gather Water Recovery System Waste Water Tank Drain Init Handover KORREKTSIYA. NEUROIMMUNITET. Experiment setup ПТАБ-1М Temperature Check (pos. А308). Tagup with specialists Water Recovery System Waste Water Tank Drain Termination with Sample Delta file prep Countermeasures System (CMS) Advanced Resistive Exercise Device (ARED) Quarterly Inspection IDENTIFICATION. Copy ИМУ-Ц micro-accelerometer data to laptop Multi-user Droplet Combustion Apparatus MWA Prep HRF Generic Urine Collection Setup Water Resource Management (WRM) Condensate Sample Terminate HRF Generic Frozen Blood Collection Setup Relocating emergency mask bags. Story Time From Space Historical Photo Story Time Weightless Read Environmental Health System (EHS) – Coliform Water Sample Analysis 44 +/- 4 hours post processing Portable Emergency Provisions (PEPS) Inspection (XTP) Collecting SM and FGB Air Samples Using АК-1М Sampler CONTENT. Experiment Ops. Tagup with specialists CONTENT. Experiment Ops KORREKTSIYA. Logging Liquid and Food (Medicine) Intake NEUROIMMUNITET. Saliva Sample NEUROIMMUNITET. Starting 24-hr ECG Recording. Tagup with specialists Completed Task List Items STFS Orbit Demo Habit HF Dir Obs Sub Stow Nod2 Cleanup Ground Activities All activities were completed unless otherwise noted. Nominal Ground Commanding Three-Day Look Ahead: Friday, 11/25: CIR MDCA maintenance, WHC maintenance, Eye Ultrasound, MARES EPM HD Install, COL HTV gather, Aquapad Saturday, 11/26: Housekeeping, Crew Off Duty, HRF Collection Sunday, 11/27: Crew Off Duty, HRF Collection QUICK ISS Status – Environmental Control Group: Component Status Elektron On Vozdukh Manual [СКВ] 1 – SM Air Conditioner System (“SKV1”) Off [СКВ] 2 – SM Air Conditioner System (“SKV2”) Off Carbon Dioxide Removal Assembly (CDRA) Lab Standby Carbon Dioxide Removal Assembly (CDRA) Node 3 Operate Major Constituent Analyzer (MCA) Lab Operate Major Constituent Analyzer (MCA) Node 3 Idle Oxygen Generation Assembly (OGA) Process Urine Processing Assembly (UPA) Standby Trace Contaminant Control System (TCCS) Lab Off Trace Contaminant Control System (TCCS) Node 3 Full Up