Researchers use optogenetics and mathematical modelling to identify a central molecule in cell mechanics

All cell types continually generate forces in the human body. An interdisciplinary cooperation of biologists and physicists including Heidelberg researcher Prof. Dr Ulrich Schwarz now succeeded in performing high-resolution measurements of cell forces using light to switch them on and off in a controlled manner. The scientists from the universities of Heidelberg and Chicago (USA) used optogenetics and mathematical modelling to identify a central molecule in cellular mechanics. The results of this research were published in the journal Nature Communications.