Have you ever wondered how tirelessly the tiny fruit fly buzzes around your fruit bowl? This behavior not only demands tremendous energy but also requires highly coordinated neuronal signaling that enables continuous flight. A recent study from Prof. Gaiti Hasan’s lab has uncovered molecules in fruit fly brains required for enabling flight for long periods of time and helps them locate the fruit bowl in your pantry. One of the key proteins identified in this study is the FMRFa receptor (FMRFaR). The authors describe a role for this receptor in a specific class of neurons in the adult fly brain that help the fly sustain flight for long periods of time. The study was published in PLOS Genetics.