Tales from 141,430 and one genomes

Non-invasive prenatal testing potentially provides a wealth of genetic information, but the quality of the DNA sequencing is poor — only about 10 percent coverage per genome. Nevertheless, scientists now show that with enough genomes — in this case, 141,431 — it is possible to find genetic variants linked with human traits, including birth outcomes and susceptibility to infectious disease. Such statistical analyses can even by used to track migration patterns.