Syringes and hollow needles have been used to deliver medication for more than a century. However, the precise implementation of these devices depends on the operator, and it can be difficult to deliver medication to delicate regions such as the suprachoroidal space at the back of the eye. Investigators have developed a highly sensitive intelligent-injector for tissue-targeting (i2T2) that detects changes in resistance in order to properly and safely deliver medication in preclinical testing.