Raman microspectroscopy is a laboratory technique to produce molecular fingerprints of materials and biological specimens. However, to date fluorescence has interfered with effective application of this technique and limited its use. Now Gordon Taylor, Ph.D., a Professor in the School of Marine and Atmospheric Sciences (SoMAS) at Stony Brook University, and colleagues have devised a photochemical technique that suppresses fluorescence in sample preparation. This new technique may open the door to more efficient and highly resolved investigations of chemical distributions within individual cells. Their findings are published in Scientific Reports.
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Source: Phys.org