Researchers at Massachusetts General Hospital (MGH) have uncovered new clues that add to the growing understanding of how female mammals, including humans, ‘silence’ one X chromosome. Their new study, published in Molecular Cell, demonstrates how certain proteins alter the architecture of the X chromosome, which contributes to its inactivation. Better understanding of X chromosome inactivation could help scientists figure out how to reverse the process, potentially leading to cures for devastating genetic disorders.
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Source: Phys.org