Nearly all vital functions in the human body are regulated by so-called G protein-coupled receptors on the cell surface. These receptors thus serve as attractive drug targets to treat various diseases. Researchers have now discovered that empty spaces inside these receptors are important for their activation and thus for relaying messages to the inner cell. Their approach to locate these voids may help to direct the search for novel drugs.
Click here for original story, Researchers determine activation mechanism of G protein–coupled receptors
Source: Phys.org