In a Proceedings of the National Academy of Sciences (PNAS) “Special Feature” paper published online June 26, Lawrence Livermore National Laboratory (LLNL) and University of Michigan researchers reported on recent experiments and techniques designed to improve understanding and control of hydrodynamic (fluid) instabilities in high energy density (HED) settings such as those that occur in inertial confinement fusion implosions on the National Ignition Facility (NIF).